Amino acids

L-Carnitine

Also known as: carnitine, levocarnitine, acetyl-L-carnitine, ALCAR, propionyl-L-carnitine

A compound that shuttles fatty acids into mitochondria. Prescription IV levocarnitine treats true deficiency; wellness 'fat-burner' drips are unproven.

Medically reviewed by Akash Bhagat, DO, FACEP

· Published by NeuMed Modern Urgent Care + IV Therapy

What the evidence supports

UseEvidence
Primary or dialysis-related carnitine deficiency (prescription levocarnitine) Established
Weight loss or athletic fat-burning via wellness IV Unproven

Common side effects

  • Fishy body odor
  • Nausea
  • Stomach cramps
  • Vein irritation

Who should be cautious or avoid this

  • Seizure history — carnitine has been associated with increased seizure activity in susceptible people
  • Severe kidney disease outside a nephrology plan
  • Thyroid disease — discuss with a clinician

What it is

L-carnitine carries long-chain fatty acids into mitochondria so they can be burned for energy. Your liver and kidneys make it from lysine and methionine; meat supplies the rest. Levocarnitine is the prescription form used when the body can’t keep levels up (certain genetic disorders, long-term hemodialysis).

Why it’s used in IV therapy

Marketed in athletic and weight-loss drips as a fat-burner, sometimes alongside Lipo-B.

What the evidence says

IV levocarnitine is established for diagnosed deficiency. Healthy people make and eat enough. Oral carnitine for athletic performance and weight loss has mixed, mostly disappointing results; there is no good evidence a wellness IV dose burns fat or improves workouts.

Side effects and cautions

A fishy odor is a known, harmless-if-embarrassing effect. Nausea is common. People with a seizure disorder should not add carnitine casually. This is not the same product as a Lipo-B / MIC shot, even when clinics sell them together.

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Sources

  1. NIH ODS — Carnitine Fact Sheet for Health Professionals

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